Search This Blog

PROTEIN STABILITY PROGRAM

   PROTEIN STABILITY COPYRIGHTED PROGRAM
   VIRTUAL QUANTIFICATION OF PROTEIN STABILITY USING
    APPLIED KINETIC AND THERMODYNAMIC PARAMETERS



Developed by S.Prasanth Kumar
© PRASANTH VIRTUAL BIOINFO LAB. All Rights Reserved, 2011.

Abstract
Protein stability, the most important aspect of molecular dynamics and simulations, requires sophisticated instrumentations of molecular biology to analyze its kinetic and thermodynamic background. Sequence- and structure-based programs on protein stability exist which relies only on single point mutations and sequence optimality. The energy distribution conferred by each amino acid essentially paves way for understanding protein stability. To the best of our knowledge, Protein Stability is a first program of its kind, developed to explore the energy requirement of each amino acid in the protein sequence derived from various applied kinetic and thermodynamic quantities. The algorithm is strongly dependent both on kinetic quantities such as atomic solvation energies and solvent accessible surface area and thermodynamic quantities viz. enthalpy, entropy, heat capacity, etc. The hydrophobicity pattern of protein was considered as the important component of protein stabilization. A program was developed to provide the energy distribution and its overall stability.

Read the Full Text Article here:
http://iioablett.pitt.edu/ojs/index.php/iioablett/article/view/12.

MIRROR SITE:
http://virtualprotstab.webs.com

MANUAL:
You can download the manual here:        
http://www.4shared.com/document/sI-fgdiN/Protein_Stability_Manual.html
or read online (requires Java enabled browser)
http://www.slideshare.net/prasanthperceptron/protein-stability-manual-8432452


FREE DOWNLOAD:
(DISTRIBUTED UNDER CREATIVE COMMON RIGHTS)
Kindly download the Stand-alone Program from this external mirror:
http://www.4shared.com/zip/FAjp6NNS/protein_stability.html
{Program size: 434.82 KB; Average Download Time in Free Mode: 11 Seconds}

Now on Softpedia:
http://www.softpedia.com/get/Science-CAD/Protein-Stability.shtml 


Grant of 100% Clean Award to Protein Stability Program

Thanks to the Softpedia Database and its Editorial Team for considering the Protein Stability Program to be available as a freeware, added to the database and granted "100% Clean Award"










FEEDBACKS/COMMENTS/QUERIES:
I value every feedback, comments to improve the program, queries and troubleshooting tips.
Just mail me at prasanthbioinformatics@gmail.com



Subscribe to: Posts (Atom)